What is 2 amino pyridine?

2-Aminopyridine

2-Aminopyridine is an organic compound with the formula H₂NC₅H₄N. It is one of three isomeric aminopyridines, the others being 3-aminopyridine and 4-aminopyridine. It is a derivative of pyridine with an amino group at the 2-position.

Properties

Formula: C₅H₆N₂
Molar mass: 94.12 g/mol
It is a solid at room temperature.
It has a melting point of approximately 57-60 °C.
It is soluble in water and organic solvents.
It is a weak base due to the lone pair of electrons on the nitrogen atom.

Synthesis

2-Aminopyridine can be synthesized through several methods including:

Chichibabin reaction: This is a classic method involving the reaction of pyridine with sodium amide.

Uses

2-Aminopyridine and its derivatives are used in a variety of applications including:

Pharmaceuticals: It is a useful building block in the synthesis of various pharmaceutical compounds.
Agrochemicals: Used in the synthesis of agrochemicals such as pesticides.
Ligand in coordination chemistry: It can act as a ligand to form coordination complexes with metal ions.
Chemical research: It is also widely used in chemical research as a versatile reagent and intermediate.

Safety

As with many organic compounds, 2-aminopyridine should be handled with care. Appropriate safety precautions, such as wearing gloves and eye protection, should be taken. Specific hazard information should be consulted from the material safety data sheet (MSDS).